Reviews and ratings for wellbutrin when used in the treatment of depression. Long story short, Im never getting off of it again, BUT if someone is trying to get on. Sure Wellbutrin has caused me to lose some weight, but thats because I can hardly eat!. What is difference between Wellbutrin, Wellbutrin SR, and XL? Hello there, My doctor just prescribed to me Wellbutrin XL and I was. hoped that it would help me lose weight and gain more energy for exercise, I didnt. Long story short, I got off of the phentermine and went on Wellbutrin. Dr Artem Agafoanswered this Wellbutrin for Weight Loss. i have taken welbutrin XL (300 mg) for 4 months and i noticed a rapid weight loss and a marked decrease in my appetite but i think it also. and thats my story. I Am On Wellbutrin A true, personal story from the experience, I Am On Wellbutrin. I started on Bupropion SR 150, and I will be increasing to Bupropion XL 300 soon. Lastly, I did have more energy and weight loss when I was on it the first. I am looking for those that have been on it while trying to lose weight - any success?. I was switched to wellbutrin xl and have lost that weight.